Frog Skin Has Antimicrobial Effects

Frogs protect themselves against pathogenic microorganisms by means of several different types of antimicrobial peptides called temporins. Frogs secrete temporins from their skin, which kills fungi and viruses by poking holes in their cell membranes.

Defense/Stability:: Microbe/germ resistance

Long life

Mangoni ML et al., Effects of the antimicrobial peptide temporin L on cell morphology, membrane permeability and viability of Escherichia coli., Biochem J. ,　380, 859-865, 2004

Frog skin’s antimicrobial strategy can be used to develop durable paints and coating materials, as well as long-lasting building materials, wood antiseptics, and new medicines.

African Clawed Frog’s Skin Have Antibacterial Effects: African clawed frog’s skin produces the antibiotic peptide magainin which protects the frog from bacterial and fungal infections by destroying bacterial and fungal cell membranes.

Query	Affected	Num. rows	Took (ms)	Actions
SHOW FULL COLUMNS FROM `contents`	16	16	13	maybe slow
SELECT CHARACTER_SET_NAME FROM INFORMATION_SCHEMA.COLLATIONS WHERE COLLATION_NAME= 'utf8_general_ci';	1	1	1
SHOW FULL COLUMNS FROM `users`	10	10	4	maybe slow
SHOW FULL COLUMNS FROM `groups`	4	4	2	maybe slow
SHOW FULL COLUMNS FROM `permissions`	5	5	10	maybe slow
SHOW FULL COLUMNS FROM `groups_permissions`	3	3	2	maybe slow
SHOW FULL COLUMNS FROM `groups_users`	3	3	2	maybe slow
SHOW FULL COLUMNS FROM `contents_searches`	6	6	13	maybe slow
SHOW FULL COLUMNS FROM `attachments`	11	11	3	maybe slow
SHOW FULL COLUMNS FROM `attachments_revs`	13	13	3	maybe slow
SHOW FULL COLUMNS FROM `contents_related_items`	5	5	2	maybe slow
SHOW FULL COLUMNS FROM `related_items`	6	6	2	maybe slow
SHOW FULL COLUMNS FROM `contents_related_items_revs`	8	8	2	maybe slow
SHOW FULL COLUMNS FROM `contents_tags`	5	5	13	maybe slow
SHOW FULL COLUMNS FROM `tags`	7	7	6	maybe slow
SHOW FULL COLUMNS FROM `tag_groups`	6	6	7	maybe slow
SHOW FULL COLUMNS FROM `contents_tags_revs`	7	7	6	maybe slow
SHOW FULL COLUMNS FROM `contents_revs`	18	18	6	maybe slow
SELECT `Content`.`id`, `Content`.`user_id`, `Content`.`last_edit_user_id`, `Content`.`post_date`, `Content`.`post_date_year`, `Content`.`post_date_month`, `Content`.`post_date_day`, `Content`.`title`, `Content`.`title_en`, `Content`.`content`, `Content`.`plain_content`, `Content`.`page_view`, `Content`.`flag`, `Content`.`mod_count`, `Content`.`created`, `Content`.`modified` FROM `contents` AS `Content` WHERE `id` = 83 LIMIT 1	1	1	0
SELECT `Attachment`.`file_name`, `Attachment`.`dir`, `Attachment`.`model`, `Attachment`.`foreign_key` FROM `attachments` AS `Attachment` WHERE `file_name` <> 'default.jpg' AND `Attachment`.`foreign_key` = (83)	1	1	0
SELECT `ContentsRelatedItem`.`content`, `ContentsRelatedItem`.`related_item_id`, `ContentsRelatedItem`.`content_id` FROM `contents_related_items` AS `ContentsRelatedItem` WHERE `ContentsRelatedItem`.`content_id` = (83)	12	12	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 1	1	1	5	maybe slow
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 2	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 5	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 6	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 7	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 8	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 9	1	1	13	maybe slow
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 9	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 9	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 11	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 4	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 12	1	1	0
SELECT `ContentsTag`.`id`, `ContentsTag`.`tag_group_id`, `ContentsTag`.`mod_count`, `ContentsTag`.`tag_id`, `ContentsTag`.`content_id` FROM `contents_tags` AS `ContentsTag` WHERE `ContentsTag`.`content_id` = (83)	2	2	1	maybe slow
SELECT `Tag`.`name`, `Tag`.`comment`, `Tag`.`tag_group_id` FROM `tags` AS `Tag` WHERE `Tag`.`id` = 72	1	1	11	maybe slow
SELECT `TagGroup`.`code`, `TagGroup`.`name` FROM `tag_groups` AS `TagGroup` WHERE `TagGroup`.`id` = 6	1	1	0
SELECT `Tag`.`name`, `Tag`.`comment`, `Tag`.`tag_group_id` FROM `tags` AS `Tag` WHERE `Tag`.`id` = 99	1	1	0
SELECT `TagGroup`.`code`, `TagGroup`.`name` FROM `tag_groups` AS `TagGroup` WHERE `TagGroup`.`id` = 7	1	1	3	maybe slow
SELECT `RelatedItem`.`id`, `RelatedItem`.`code`, `RelatedItem`.`name`, `RelatedItem`.`created`, `RelatedItem`.`modified`, `RelatedItem`.`flag` FROM `related_items` AS `RelatedItem` WHERE `code` = 'function' LIMIT 1	1	1	0
SELECT `Content`.`id`, `Content`.`title`, `Content`.`title_en` FROM `contents` AS `Content` WHERE id = (87) ORDER BY `id` desc	1	1	29	maybe slow
SELECT `Attachment`.`file_name`, `Attachment`.`dir`, `Attachment`.`foreign_key` FROM `attachments` AS `Attachment` WHERE `file_name` <> 'default.jpg' AND `Attachment`.`foreign_key` = (87)	1	1	0
SELECT `ContentsRelatedItem`.`content`, `ContentsRelatedItem`.`related_item_id`, `ContentsRelatedItem`.`content_id` FROM `contents_related_items` AS `ContentsRelatedItem` WHERE `related_item_id` = '1' AND `ContentsRelatedItem`.`content_id` = (87)	1	1	0
SELECT `RelatedItem`.`code`, `RelatedItem`.`name` FROM `related_items` AS `RelatedItem` WHERE `RelatedItem`.`id` = 1	1	1	0

Message	Memory use
Component intitailization	6.79 MB
Controller action start	6.83 MB
Controller render start	6.90 MB
View render complete	7.93 MB

Message	Time in ms	Graph
Core Processing (Derived)	615.73
Component initialization and startup	22.43
Controller action	109.66
Render Controller Action	108.02
» Rendering View	94.49
» » Rendering APP/views/contents/view.ctp	40.42
» » Rendering APP/views/layouts/default.ctp	47.40
» » » Rendering APP/views/elements/header.ctp	6.46
» » » Rendering APP/views/elements/content_sidebar.ctp	0.45
» » » Rendering APP/views/elements/footer.ctp	0.54

Frog Skin Has Antimicrobial Effects

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